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Emeritus Faculty

The following faculty members are faculty or continuing professionals who retired in good standing after 15 years or more, and who have been awarded Emeritus status by the President of the University of Arizona.  Please click on the name of each member to learn more about them.  

Ronald E. Allen Ph.D. (Muscle Biology, Animal Sciences, Skeletal Muscle)

Program Affiliations:  Animal Sciences, Nutritional Sciences, Physiological Sciences

Website and Publications:

Research Interests:  Muscle Biology, Animal Sciences, Skeletal Muscle

  • The focal point of research in this laboratory is the growth and repair of skeletal muscle in domestic animals and humans. The key player in both of these processes is the satellite cell. Satellite cells are muscle stem cells that are generally found in a quiescent, or dormant, state in close association with muscle fibers. Although sparsely distributed in postnatal muscle, they play an important role in regulating muscle growth by dividing and fusing with existing muscle fibers. The result is a net increase in the number of muscle fiber nuclei and hence, an increase in the growth potential of the fiber. In injured muscle, satellite cells are stimulated to divide and form new fibers that replace damaged muscle fibers. Consequently, the rate and efficiency of muscle growth and repair are dependent on the activity of satellite cells, and therefore, satellite cell function is relevant to muscle growth in domestic animals, to human muscle disease and injury and to problems associated with aging
  • Research goals in this laboratory have been to identify the hormones and growth factors responsible for satellite cells activation from the quiescent state, division and fiber formation. This problem is being approached by integrating experiments at the cellular, tissue, and whole animal level.

Eldon Braun, PhD. (Comparative Renal Physiology)

Program Affiliations:  Physiology, Bio5 Institute, Physiological Sciences

Website and Publications:

Research Interests:  Comparative Renal Physiology

  • Comparative renal physiology and morphology; regulation of individual nephron filtration rates and renal blood flow.

William Dantzler, M.D., PhD. (Renal Physiology)

Program Affiliations:  Physiology, Bio5 Institute, Physiological Sciences

Website and Publications:

Research Interests:  Renal Physiology, Cation and Anion Transport

  • Relationship of structural organization of thin limbs of Henle's loops to function in mammalian renal inner medulla.

  • Recycling of amino acids and organic osmolytes between Henle's loops and vasa recta in mammalian renal inner medulla.

  • Regulation of intracellular pH in thin limbs of Henle's loops in mammalian renal inner medulla.

  • Cellular and molecular mechanisms and regulation of organic anion and cation transport in renal proximal tubules of mammals, birds, and reptiles.

Erik Henriksen, PhD. (Diabetes: Regulation of Glucose Transport, Insulin)

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Program Affiliations:  Physiology, Biochemistry and Molecular & Cellular Biology, Nutritional Sciences, Bio5 Institute, Physiological Sciences

Website and Publications:  Sarver Heart Center Profile

Research Interests:  Diabetes: Regulation of Glucose Transport, Insulin

  • Regulation of glucose transport in muscle by insulin and contractions
  • Role of glycogen synthase kinase-3 in the etiology of skeletal muscle insulin resistance
  • Role of oxidative stress in the development of defective insulin signaling and glucose
    transport in skeletal muscle
  • Pharmaceutical and nutriceutical interventions for the treatment of insulin resistance of
    skeletal muscle glucose transport
  • Adaptive responses of carbohydrate and protein metabolism in muscle to exercise,
    simulated weightlessness, and denervation

Patricia B. Hoyer Ph.D. (Ovarian Physiology/Toxicology, Menopause)

Program Affiliations:  Physiology, Pharmacology & Toxicology, Animal Sciences, Physiological Sciences

Website and Publications:

Research Interests:  Ovarian physiology/toxicology, menopause

  • Elucidating signaling pathways that regulate cell death by apoptosis
  • Establishing mechanisms of ovotoxicity caused by environmental chemicals
  • Developing models that alter the rate of atresia in ovarian follicles
  • Characterizing a chemically-induced follicle-depleted ovary-intact rodent for peri- and post- menopause

Terry Landowski, PhD. (Cancer: Therapeutic Development)

Program Affiliations:  Arizona Cancer Center, Physiological Sciences

Website and Publications:  Cancer Center Profile

Research Interests:  Cancer: Therapeutic Development

Douglas F. Larson Ph.D. (Hypertension: Immune System, Left Ventricular Function)

Program Affiliations:  Department of Surgery, Biomedical Engineering, Medical Pharmacology, Bio5 Institute, Physiological Sciences

Website and Publications:  Department of Surgery Faculty Page

Research Interests:  Hypertension: Immune System, Left Ventricular Function

  • The goal of my research is to define the relationship between the immune system and the left ventricular function. Recently, research activities have focused on the role of the immune system and its regulation of gene expression and enzyme function in cardiomyopathies. The models of cardiomyopathy being studied are secondary to HIV infection, infarction, rejection and aging. The hypothesis of these studies is that myocardial dysfunction secondary to an immune-cytokine event is mediated by increased iNOS and NO activity. In support of these studies, we have developed a system that can quantify the ventricular mechanics of the murine heart in vivo.

 

Richard Levine, PhD. (Neuroscience: Systems, Steroid Hormones, Electrophysiology)

Program Affiliations:  Neuroscience, Bio5 Institute, Physiological Sciences

Website and Publications:

Research Interests:  Neuroscience: Neuromuscular Systems, Steroid Hormones, Electrophysiology

  • People in the Levine laboratory share a common interest in the function and development of neuromuscular systems. Neuromuscular systems, including the motoneurons that control movement and the muscles that they innervate, are modified throughout life by many factors including hormones, learning, training, and aging. We are using the molecular and genetic power of Drosophila, and mammalian systems to explore the neural circuits that control movement and the mechanisms through which steroid hormones regulate their function and postembryonic modification. Using techniques such as intracellular and whole-cell patch recording, dye injection, confocal microscopy and cell culture we are describing the biophysical properties, dendritic anatomy, and synaptic connections of individual motoneurons. Recent experiments explore the role of calcium and potassium currents in determining the functional properties of identified motoneurons that participate in locomotor and respiratory behavior